July 2026 in “Journal of Medical Imaging and Radiation Oncology” This study reviewed evidence on cutaneous reactions and associated radiation doses from cranial or spinal neurointerventional procedures, finding that alopecia/epilation was most common and onset doses often aligned with known thresholds, highlighting the need for standardized dose reporting and follow-up.
May 2019 in “Journal of clinical oncology” This study found that concurrent chemotherapy with radiotherapy may increase the risk of grade 2 persistent radiation-induced alopecia, while topical minoxidil showed potential benefits, though more research is needed on its efficacy.
June 2026 in “EJC Paediatric Oncology” In this retrospective study on pediatric craniospinal irradiation, researchers found that permanent radiation-induced alopecia occurred in 45.8% of patients, with higher radiation doses and treatment intensity being significant predictors, suggesting that defined dosimetric thresholds can support scalp-sparing planning.
November 2019 in “Neuro-oncology” This study found that using rind-based dosimetric techniques in brain irradiation significantly reduced scalp dose and alopecia compared to standard treatment plans, with 60% of patients experiencing no hair loss.
July 2026 in “Open Science Framework” This review identifies higher radiation doses and larger scalp exposure as major factors in radiation-induced alopecia, highlights prevention techniques like IMRT and proton therapy, and discusses management options such as minoxidil and hair transplantation, but notes limited evidence for these treatments.
