Serum Clusterin Level in Post-Adolescent Acne

The study investigates the role of serum clusterin as a potential diagnostic and predictive biomarker for post-adolescent acne, which is increasingly common, particularly in women. Serum clusterin, a multifunctional glycoprotein, is examined for its involvement in systemic disorders, inflammation, immunology, the NFB pathway, apoptosis, and dermatological diseases. The findings suggest that serum clusterin may significantly contribute to the inflammatory and immunological processes underlying acne, although its exact mechanisms in acne pathogenesis remain to be fully elucidated.