Screening the Chemical Composition and Bioactivity of Cerasus Serrulata Flower Extracts Using Two Extraction Methods
July 2023
in “Pharmacognosy Magazine”
TLDR Cerasus serrulata flower extracts have strong antibacterial and antioxidant effects and may help prevent hair loss.
The study examined the chemical composition and bioactivity of Cerasus serrulata flower extracts, obtained through two methods: low-temperature vacuum extraction and ethanol extraction. The extracts were rich in alkanes and aromatic compounds, with benzaldehyde being the main component in the cold vacuum extraction and pipecolic acid in the ethanol extract. The extracts demonstrated strong antibacterial properties and excellent free radical scavenging ability. In a mouse model of alopecia, the extracts significantly altered protein levels in the skin, inhibited Vascular Endothelial Growth Factor (VEGF) reduction, increased β-catenin, Fibroblast Growth Factor Receptor (FGFR), and Insulin-like Growth Factor 1 (IGF-1) gene expression, and reduced 5α-reductase and dihydrotestosterone (DHT). The study suggests that C. serrulata extract could be beneficial as natural antioxidative, antibacterial, and anti-alopecia agents.
View this study on journals.sagepub.com →
Cited in this study
research Phytochemical Constitution, Anti-Inflammation, Anti-Androgen, and Hair Growth-Promoting Potential of Shallot (Allium Ascalonicum L.) Extract
research Hair Growth-Promoting Effects of Sargassum Glaucescens Oligosaccharides Extracts
Extracts from a type of brown seaweed can help promote hair growth.
research Hair Regeneration Effects of Lespedeza bicolor Extract In Vivo and In Vitro
Lespedeza bicolor extract promotes hair growth and increases hair follicle cell growth, potentially making it a better treatment than minoxidil.
research Effects on Steroid 5-Alpha Reductase Gene Expression of Thai Rice Bran Extracts and Molecular Dynamics Study on SRD5A2
Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.
research A Botanical Compound for the Treatment of Alopecia Areata and Chemotherapy-Induced Alopecia
research Hair Growth Promoting Effect of <i>Hottuynia cordata</i> Extract in Cultured Human Hair Follicle Dermal Papilla Cells
Houttuynia cordata extract may help hair grow by improving cell survival and increasing cell growth.
research In vivo and in vitro evaluation of hair growth potential of Cacumen Platycladi, and GC-MS analysis of the active constituents of volatile oil
research Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth-Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development
Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.
research Exploring the combination and modular characteristics of herbs for alopecia treatment in traditional Chinese medicine: an association rule mining and network analysis study
Certain herbal combinations in traditional Chinese medicine might be effective for treating hair loss, focusing on liver or stomach health.
research Naturally Occurring Hair Growth Peptide: Water-Soluble Chicken Egg Yolk Peptides Stimulate Hair Growth Through Induction of Vascular Endothelial Growth Factor Production
Chicken egg yolk peptides can promote hair growth by increasing a specific growth factor.
research The effectiveness of treatments for androgenetic alopecia: A systematic review and meta-analysis
Minoxidil, finasteride, and low-level laser light therapy effectively treat hair loss.
research Androgenetic alopecia: a review
Male pattern baldness involves genetics, hormones, and needs better treatments.
research Androgenetic Alopecia: An Update Of Treatment Options
Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.