Scalable Fabrication, Compartmentalization, and Applications of Living Microtissues
April 2022
in “
Bioactive Materials
”
Studysummary This review discusses the current techniques for engineering microtissues, emphasizing the potential of continuous microfluidic processes to facilitate large-scale production, but reports no new experimental results.
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The document reviewed the use of living microtissues, which more closely resembled native tissue physiology than 2D cultures, in various applications from biological research to industrial uses like cruelty-free meat production. It highlighted the challenge of scaling up microtissue production for industrial and clinical settings due to limitations in current techniques. The review emphasized the potential of continuous microfluidic processes to overcome these limitations by offering higher throughput and reproducible control over microtissue composition and size. It concluded with an outlook on necessary developments for enabling large-scale microtissue fabrication using continuous processes.
