Saw palmetto extract: A dermatologist's perspective

The document from 2016 discussed the use of Saw palmetto extract (SR), a natural herb, in dermatology, particularly for the treatment of androgenic alopecia. SR is believed to have antiandrogenic properties and is thought to block the enzyme 5 alpha reductase, preventing the conversion of testosterone to dihydrotestosterone (DHT), a primary cause of hair loss. It was found effective in managing androgenetic alopecia (AGA), potentially reducing hirsutism, and influencing the production of sebum, which contributes to acne. However, the safety and efficacy of SR had not been sufficiently investigated at the time, with side effects including mild stomach discomfort and potentially serious hepatic inflammation. The document also highlighted a lack of regulation and evidence about its efficacy and safety, particularly for long-term use.