Review on Seasonal Incidence of Psoriasis Exacerbations During Winter in India: Clinical Insights and Observations

    December 2024 in “ Journal of Population Therapeutics and Clinical Pharmacology ”
    Dhwiti Patel
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    TLDR Psoriasis worsens in winter in India due to less sunlight and dry skin, needing personalized treatment.
    The review article discusses the seasonal exacerbation of psoriasis during winter in India, affecting 30% of patients due to reduced sunlight exposure and increased skin dryness. Psoriasis, impacting 125 million people globally, is linked with comorbidities like inflammatory arthritis and cardiometabolic diseases. The prevalence varies, with adult rates from 0.53% to 11.48% and children's rates from 0.5% to 1.40%. The article emphasizes the role of cytokines and immune cells in the disease's pathophysiology and highlights lifestyle factors such as alcohol consumption, smoking, stress, and diet that influence its progression. Effective management requires personalized treatment plans that consider seasonal changes, combining systemic medications, lifestyle adjustments, and topical therapies. The complexity of psoriasis is due to environmental factors, immune dysregulation, and genetic predisposition, with ongoing research aimed at improving treatment strategies and understanding the condition.
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