TLDR Non-hairy skin cells might be used to regenerate hair, helping with baldness and skin wounds.
The study observed hair follicle-like cells during the culture of epidermal basal keratinocytes from afollicular human foreskin samples of 30- and 12-year-old males. Three distinct cells resembling hair follicles were identified, showing characteristics similar to hair bulb, root sheath, and hair shaft, and undergoing phases akin to hair growth cycles. Despite the loss of these cells due to an incubator breakdown, the findings suggested a potential framework for inducing hair formation from non-hairy skin cells. This research provided a novel perspective on autologous hair regeneration, potentially benefiting conditions like baldness and skin wounds.
131 citations
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July 2009 in “Experimental Dermatology” The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.
96 citations
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April 2007 in “Journal of Investigative Dermatology” Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.
41 citations
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July 2002 in “Clinical and Experimental Dermatology” Effective hair loss assessment requires a mix of precise measurement methods.
14 citations
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December 1991 in “PubMed” The document explains how hair follicles develop in humans.
95 citations
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July 2006 in “British Journal of Dermatology” Vitamin D receptors in hair follicles change with the hair cycle, affecting hair growth.
56 citations
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July 2005 in “Experimental Dermatology” Injected human hair follicle cells can create new, small hair follicles in skin cultures.
January 2003 in “Chinese Journal of Reparative and Reconstructive Surgery” Dermal papilla cells can help form hair follicles and produce hair.
61 citations
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October 1996 in “Development” Hair growth can be stimulated by combining certain skin cells, which can rejuvenate old cells and cause them to specialize in hair follicle creation.
94 citations
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February 1994 in “The journal of investigative dermatology/Journal of investigative dermatology” EGF makes hair follicles grow longer but stops hair production.