Findings from the Assessment of Real-World Disease Characteristics and Outcomes in Alopecia Areata in a Global Non-Interventional Observational Cohort (ADAAGIO) Study
TLDR Most patients with alopecia areata did not achieve lasting hair regrowth despite treatment.
The ADAAGIO study assessed real-world disease characteristics and outcomes in 741 patients with alopecia areata (AA) with ≥ 50% scalp hair loss in Europe. The study found that while patients experienced a mean absolute SALT score reduction of 44.6% at 12 months, only 10.6% achieved and sustained a SALT score ≤ 20 for at least 6 months. The most common treatment was topical corticosteroids, used by 55.6% of patients. Despite various treatments, the findings suggest potential suboptimal effectiveness in achieving sustained improvement in AA.