Rare Presentation of Concomitant Alopecia Areata and Vitiligo in a Teenager
May 2021
in “
Skin
”
TLDR A teenager had both alopecia areata and vitiligo, which are rare to occur together.
A 13-year-old Caucasian female presented with alopecia areata (AA) and later developed vitiligo, a rare co-occurrence of these autoimmune skin diseases. Initially treated with topical mometasone and prednisolone, she showed new hair depigmentation at a 3-month follow-up, leading to a diagnosis of concomitant vitiligo and the addition of topical tofacitinib. This case highlighted a potential pathogenic link between AA and vitiligo, involving CD8+ cytotoxic T-cells, interferon gamma (IFN-ɣ), and IFN-ɣ-induced chemokines. The co-localization of these conditions posed therapeutic challenges and significant psychological distress for the patient.
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