Standardization, Validation, And Application Of A Rapid And Reliable HPLC-UV Method For The Determination Of Minoxidil And Minoxidil Oxothiazolidinecarboxylate In Hair Growth Products

    January 2025
    Madelen López-López, Diana Maritza Torres-Lizarazo, Tatiana Ramírez Alzate, Juan Camilo Mejía‐Giraldo
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    Studysummary This study validated an HPLC-UV method to detect minoxidil in cosmetic products and found that 2 out of 9 analyzed products contained minoxidil, despite international regulations banning its inclusion due to potential systemic absorption.
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    The document details the development and validation of a rapid and reliable HPLC-UV method for determining the presence of minoxidil and minoxidil oxothiazolidinecarboxylate in hair growth products. The study emphasizes the importance of standardizing analytical methods to ensure the quality and efficacy of hair growth treatments. The validated method demonstrated high precision, accuracy, and sensitivity, making it suitable for routine analysis in quality control laboratories. This advancement supports the consistent production of effective hair growth products by providing a robust tool for monitoring active ingredient concentrations.
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