Microneedling With Triamcinolone Acetonide Versus Intralesional Triamcinolone Acetonide in Treatment of Alopecia Areata

    February 2023
    Bothina Abd El Naby Ibrahim Ageeba, Amr Mohamed Zaki, Emad Mahmoud El Rewiny
    From the encyclopedia
    Microneedling →

    technique to create small wounds in skin to activate collagen production and hair growth

    Alopecia Areata →

    autoimmune disorder causing patchy hair loss

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    Studysummary This study observed that both intralesional triamcinolone acetonide and microneedling with triamcinolone acetonide significantly reduced alopecia areata severity, with no significant difference in effectiveness between the two treatments, suggesting microneedling as an effective and less invasive option.
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    The study compared the effectiveness of intralesional triamcinolone acetonide versus microneedling with triamcinolone acetonide for alopecia areata treatment in 50 patients. The results showed a statistically significant reduction of the SALT score and all dystrophic hair markers of alopecia areata by dermoscopy at the end of the study versus baseline in both groups. However, the difference between the microneedling group and the intralesional group concerning clinical response was statistically insignificant. The study concluded that microneedling, especially when combined with Triamcinolone acetonide, is an effective treatment for alopecia areata, providing a comparatively inexpensive, safe, less painful, less invasive tool with no serious complications.
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