Histological and Ultrastructural Evaluation of the Effect of Platelet Rich Plasma (PRP) on Wound Healing in the Tongue of Normal and Streptozotocin-Induced Diabetic Albino Rats

October 2020 in “ Egyptian Dental Journal /Egyptian Dental Journal ”

Mary Ramzy, Tarik Essawy, Ali Shamaa, Saher Mohammed

Platelet Rich Plasma PRP wound healing Streptozotocin

TLDR PRP speeds up tongue wound healing in both diabetic and non-diabetic rats.

The study evaluated the effect of Platelet Rich Plasma (PRP) on tongue wound healing in 108 normal and Streptozotocin-induced diabetic albino rats. The rats were divided into non-diabetic and diabetic groups, with subgroups receiving PRP treatment either before or after wounding. Histological and ultrastructural examinations showed that the most rapid healing occurred in subgroups treated with PRP before wounding, with significant healing observed by the 3rd day post-operation. Complete healing was noted by the 7th day in subgroups treated with PRP after wounding, similar to non-diabetic controls. Diabetic rats without PRP treatment showed delayed healing, completing by the 10th day. The study concluded that PRP application, either before or after wounding, enhanced wound healing in both diabetic and non-diabetic oral mucosal wounds.

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research Systematic Review of Platelet-Rich Plasma (PRP) Preparation and Composition for the Treatment of Androgenetic Alopecia

37 citations , May 2018 in “Journal of Cosmetic Dermatology”

PRP shows promise for hair loss treatment, but needs standardized preparation and composition.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 43 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

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community Thoughts on platelet-rich plasma therapy

in Treatment 3 upvotes 1 year ago

Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

community Nice & pure PRP, 3 ml of this is going to the scalp.

in Research/Science 32 upvotes 3 years ago

The use of PRP to treat hair loss and its potential effectiveness when combined with 5 alpha reductase blockers such as Minoxidil or Finasteride.

community 2025 Official beginner guide for “I’m losing my hair, what can I do?”

in General 906 upvotes 1 year ago

For hair loss, start with Finasteride, Minoxidil, Ketoconazole shampoo, and Microneedling. For severe cases, consider Dutasteride, oral Minoxidil, or hair transplants.

community 2-month progress: Ket 3x a week, Min 2x a day, Dut 0.5 every other day, Vit D 125mcg daily, and PRP once a month.

in Progress Pictures 465 upvotes 4 years ago

User's 2-month progress with hair loss treatment includes Ket 3x a week, Min 2x a day, Dut 0.5 every other day, Vit D 125mcg daily, and PRP once a month. Users discuss treatment effectiveness, side effects, and alternative solutions.

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research Evaluation of the Effect of Platelet-Rich Plasma on Wound Healing in the Tongue of Normal and Streptozotocin-Induced Diabetic Albino Rats: Histological, Immunohistochemical, and Ultrastructural Study

4 citations , September 2020 in “Open Access Macedonian Journal of Medical Sciences”

A single PRP injection speeds up wound healing in both diabetic and non-diabetic rats.

Reviewing and Exploring the Prospects of Platelet-Rich Plasma Therapy in Pediatric Surgical Wound Management