Efficacy of Different Doses of Platelet-Rich Plasma for Moderate Carpal Tunnel Syndrome: Study Protocol for a Prospective, Randomized, Controlled Trial

This abstract describes a clinical trial registered in the Chinese Clinical Trial Registry, with its first participant enrolled on September 30, 2024; no specific study outcomes are reported.

This study found that local platelet-rich plasma injection improved mid-term outcomes for carpal tunnel syndrome more effectively than other conservative treatments, although long-term effects and standardization need further research.

This study suggests that platelet-rich plasma may improve pain and function in patients with partial-thickness rotator cuff tears and tendinopathy short-term, but the long-term benefits are unclear.

This study found that a single dose of PRP with 100 billion platelets significantly reduced pain and improved knee function in patients with osteoarthritis, but did not alter joint structure on MRI.

In this pilot study on treating dorsal wrist ganglion, PRP injection showed limited effectiveness at 1-year follow-up compared to aspiration alone, with most PRP-treated patients experiencing ganglion recurrence, suggesting that an RCT would need at least 46 patients per group to further assess PRP's utility.