TLDR Mouse preputial glands are highly developed sebaceous glands that mainly secrete neutral fat droplets.
The study examined the preputial glands of albino mice, focusing on their histology, physiology, and histochemistry. Mice of various ages were used to assess the development and aging of these glands, and the effects of androgens and estrogens were tested by dividing mice into groups receiving different treatments. The study found that the mouse preputial glands are similar to those of rats but have distinct differences, such as an association with a central hair follicle and the absence of perinuclear proteinaceous granules. The glands primarily secreted lipids in the form of neutral fat droplets and were classified as excessively developed sebaceous glands of the "monocrine" holocrine type.
11 citations
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August 2000 in “Journal of Endocrinology” DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.
76 citations
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November 2009 in “Medical Clinics of North America” Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.
97 citations
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September 2016 in “Reviews in Endocrine and Metabolic Disorders” The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.
107 citations
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August 2012 in “Seminars in Cell & Developmental Biology” The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.
416 citations
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September 1997 in “Journal of Investigative Dermatology” People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.