Post-Natal Development of Rats' Offspring Treated with the Ethanol Extract of Neem Leaves (Azadirachta Indica A. Juss) During Pregnancy and Lactation

August 2015 in “ Acta Scientiarum Biological Sciences ”

Vanessa Carla Lima da Silva, Francine Maria de França Silva, Isabelle Maria Jacqueline Meunier, Tânia Maria Sarmento Silva, Valdemiro Amaro da Silva, Frederico Celso Lyra Maia

Neem Azadirachta indica ethanol extract hair growth

TLDR Neem extract is safe for pregnant or lactating rats at tested doses.

The study assessed the effects of ethanol extract of Neem leaves on the offspring of 24 female Wistar rats during pregnancy and lactation. The rats were divided into control and three experimental groups, receiving 65, 135, and 200 mg/kg of Neem extract. The results indicated no significant differences in body mass index, survival rate, or developmental milestones such as hair growth, teeth eruption, and motor activity among the groups. The Neem extract did not cause reproductive or systemic toxicity, suggesting it was safe at the tested doses for pregnant or lactating rats.

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Post-Natal Development of Rats' Offspring Treated with the Ethanol Extract of Neem Leaves (Azadirachta Indica A. Juss) During Pregnancy and Lactation

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