Porphyrinoid Photosensitizers for Targeted and Precise Photodynamic Therapy: Progress in Fabrication

This chapter provides an overview of photodynamic therapy (PDT), a technology that utilizes the interaction of light, a photosensitizer (PS), and cellular oxygen to induce cytotoxicity for treating various medical conditions, including cancer, alopecia, angina pectoris, and periodontitis. The chapter highlights the importance of targeted PDT, which enhances the accumulation of PS in specific areas while preventing its build-up in normal cells, through different targeting methods such as active, passive, and peptide-mediated targeting. The adaptability and precision of PDT make it a promising and increasingly accepted therapeutic approach for both diagnosis and treatment of diseases.