A Pilot Study of Paternal Drug Exposure: The Motherisk Experience

The study reviewed the Motherisk Program's experience with counseling on paternal drug exposure (PEx) during the peri-conception period, using data from 157,933 telephone counseling requests between 2002 and 2006. Only 249 requests (0.16%) concerned PEx, mostly referred by health professionals. The most common drugs involved were methotrexate, finasteride, azathioprine, and prednisone. The study highlighted a lack of information on the safety of PEx and emphasized the need for future research to evaluate the safety of paternal exposure to specific drugs during the peri-conception period.