Patch Testing Procedures in Patients Suffering from Suspected Allergic Contact Dermatitis to Minoxidil

January 1989

Jean‐Marie Lachapelle, Dominique Tennstedt, B. Leroy, V. Van den Haute, F. Naert

minoxidil androgenetic alopecia allergic contact dermatitis propylene glycol Regaine

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An essential vasodilator with some anti-androgenic effects

Studysummary This case study reported that two patients treated for androgenetic alopecia with Regaine® solution developed allergic contact dermatitis due to propylene glycol, highlighting the importance of testing the vehicle in patch tests.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The study examined two patients with androgenetic alopecia who developed allergic contact dermatitis after using Regaine® solution. Patch testing revealed that the dermatitis was not caused by minoxidil itself but by the vehicle propylene glycol in which minoxidil was dissolved. The study concluded that when testing for minoxidil allergies, it is crucial to consider the vehicle used, as the choice of vehicle can significantly impact the test results.

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Research cited in this study

7 / 7 results

research Allergic Contact Dermatitis from Minoxidil

13 citations , January 1988 in “Contact Dermatitis”

This article has no abstract and reports no new findings, focusing instead on allergic contact dermatitis reactions to topical Minoxidil documented in previous studies.

research Allergic Contact Dermatitis from Minoxidil

14 citations , July 1987 in “Contact Dermatitis”

This article describes cases of allergic contact dermatitis triggered by minoxidil but provides no new clinical findings.

research Topical Minoxidil Sensitization in Androgenic Alopecia

14 citations , July 1987 in “Contact Dermatitis”

This article lacks an abstract and presents no new findings, primarily discussing topical minoxidil sensitization in androgenic alopecia.

research Contact Dermatitis to Minoxidil

34 citations , September 1985 in “Contact Dermatitis”

Minoxidil can cause skin irritation like eczema and rash in some users.

research Allergic Contact Dermatitis to Minoxidil

29 citations , August 1985 in “Contact Dermatitis”

Minoxidil can cause allergic reactions like burning, itching, and red bumps.

research Topical Minoxidil Therapy and Hair Regrowth

20 citations , February 1985 in “Archives of Dermatology”

This report discusses the potential of minoxidil for treating hair loss, spurred by early findings of hair regrowth in some patients, but emphasizes the need for further research to establish its safety and efficacy.

research Alopecia Areata Treated With Topical Minoxidil

78 citations , April 1984 in “Archives of Dermatology”

This study found that 1% minoxidil topical solution led to terminal hair regrowth in some patients with alopecia areata, though it was only cosmetically acceptable in less than half of those cases.