TLDR Combining enzymes papain and chymotrypsin with laser treatment reduces facial hair more effectively than laser alone.
This study investigated the effectiveness of combining proteolytic enzymes papain and chymotrypsin with laser treatment for managing facial hirsutism in 30 adult Caucasian women. Participants were divided into two groups: one received laser treatment with enzyme iontophoresis, and the other received laser treatment alone. Results showed that the group receiving the combination treatment experienced a significantly greater reduction in hair count (48.70% decrease) compared to the laser-only group (25.60% decrease), with a p-value of 0.017. The study concludes that iontophoretic delivery of these enzymes can enhance the efficacy of laser treatments for hirsutism.
18 citations
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October 2015 in “Journal of the European Academy of Dermatology and Venereology” Topical eflornithine helps maintain hair reduction after IPL therapy in women with facial hirsutism.
2 citations
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July 1999 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Proteolytic enzymes damaged hair follicle stem cells in transgenic mice.
5 citations
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July 1999 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Proteolytic enzymes damage hair follicles by detaching stem cells.
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
298 citations
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June 2019 in “Marine Drugs” Chitosan is a sustainable, versatile ingredient in cosmetics, enhancing skin hydration and anti-aging while promoting eco-friendly practices.
29 citations
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September 2017 in “Oncology and therapy” The document provides advice on how to recognize and treat skin-related side effects of cancer drugs known as EGFR inhibitors.
9 citations
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June 1999 in “Journal of Investigative Dermatology” The HPV type 11 region activates hair-specific gene expression in mice.
5 citations
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July 1999 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Proteolytic enzymes damage hair follicles by detaching stem cells.
