Overtreatment of Transient Maternal Hyperthyroidism Resulting in Fetal Goiter

    August 2021 in “ NeoReviews ”
    Andres F. Espinoza, Eyal Krispin, Raphael C. Sun, Jimmy Espinoza, Ahmed A. Nassr, Alireza A. Shamshirsaz
    TLDR Proper diagnosis is crucial to avoid overtreatment and complications in pregnant women with hyperthyroidism.
    A 25-year-old pregnant woman treated for hyperthyroidism with propylthiouracil (PTU) developed a fetal goiter, detected at 33 weeks of gestation. Discontinuation of PTU led to a reduction in the goiter size without causing airway obstruction. The baby, delivered at 39 weeks by cesarean section, had normal thyroid function and no respiratory distress. This case underscored the need to distinguish between transient gestational hyperthyroidism and true hyperthyroidism to prevent overtreatment and complications like fetal goiter, emphasizing the importance of a multidisciplinary approach for optimal outcomes.
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