Organoids Producing Materials

    February 2025
    Quentin Moana Perrin, Ali Miserez
    TLDR Organoids can sustainably produce advanced materials with superior properties, offering solutions to global challenges.
    This review discusses the potential of organoids, self-organizing tissues, to revolutionize material production by using biological systems to create advanced materials like spider silk. These systems offer sustainable solutions to resource scarcity and global warming by utilizing renewable resources to produce materials with superior mechanical properties and biodegradability. The review highlights the use of hair-bearing organoids, derived from induced pluripotent stem cells, as an example of growing both materials and their production units. It addresses challenges in expanding organoid research to new species and scaling production, proposing simplified descriptions to tackle these issues. The review also explores synthetic and hybrid approaches, considering their ethical, societal, and technological impacts, and encourages interdisciplinary collaboration to further develop material-producing organoids for sustainable, high-value products.
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