TLDR The Orenburg goat breed has unique genetics that require more detailed research and careful breeding.
The document reviews the Orenburg goat breed, native to the Orenburg Oblast in Russia, where three types of these small ruminant animals are prevalent: Orenburg purebred gray goats, Orenburg purebred white goats, and crossbred white goats of F1 White Don × White Orenburg. Selection of these animals at local farms is based on phenotype traits such as color, weight, and length of down hair. The Orenburg goat breed has recently become a subject of genetic research, utilizing various marker systems like immunogenetic, microsatellite, mtDNA, and SNP markers. The studies highlight the unique allele pool of the Orenburg goats, indicating it as a complex dynamic genetic system, and emphasize the need for further in-depth genome research and breeding applications.
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December 2016 in “Scientific Reports” Researchers identified genes linked to coat color, body size, cashmere production, and high altitude adaptation in goats.
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June 2013 in “Nature Medicine” A protein from certain immune cells is key for new hair growth after skin injury in mice.