On the Regulation of Hair Keratin Expression: Lessons from Studies in Pilomatricomas
May 2004
in “
Journal of Investigative Dermatology
”
Research cited in this study
16 / 16 resultsresearch Immunohistochemical localization of cytokeratins and involucrin in calcifying epithelioma: comparative studies with normal skin
Calcifying epithelioma cells can differentiate into hair cortex and outer root sheath.
research Androgen Regulation of the Human Hair Follicle: The Type I Hair Keratin hHa7 Is a Direct Target Gene in Trichocytes
research HOXC13 Is Involved in the Regulation of Human Hair Keratin Gene Expression
HOXC13 is crucial for regulating hair keratin genes in hair follicles.
research Expression of ΔNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours
Overexpression of ΔNLef1 in mouse skin leads to hair loss, cysts, and skin tumors.
research The Catalog of Human Hair Keratins
Human hair keratins were cataloged, showing their roles in hair differentiation stages.
research Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin
Tcf3 and Lef1 are key in deciding skin stem cell roles.
research Expression of type I hair keratins in follicular tumours
Pilomatrixomas likely originate from the hair matrix due to changes in hair keratin expression.
research Forkhead/winged-helix transcription factor whn regulates hair keratin gene expression: Molecular analysis of theNude skin phenotype
Whn is essential for hair growth, and its malfunction causes hair loss.
research Characterization of a 300 kbp Region of Human DNA Containing the Type II Hair Keratin Gene Domain
research Whn and mHa3 are components of the genetic hierarchy controlling hair follicle differentiation
research Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation
research The Catalog of Human Hair Keratins
Human hair is made up of different keratins, some strong and some weak, with specific types appearing at various stages of hair growth.
research Regulation of a hair follicle keratin intermediate filament gene promoter
research A Novel Human Type II Cytokeratin, K6hf, Specifically Expressed in the Companion Layer of the Hair Follicle
K6hf is a unique protein found only in a specific layer of hair follicles.
research Characterization of a 190-Kilobase Pair Domain of Human Type I Hair Keratin Genes
The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.
research Characterization of LHTric-1, a new monospecific monoclonal antibody to the trichocyte keratin Ha1
Related Research
7 / 7 resultsresearch Hair Follicle-Specific Keratins And Their Diseases
Only a few hair-specific keratins are linked to inherited hair disorders.
research Keratins of the Human Hair Follicle
research Hair follicle differentiation and regulation.
Hair follicle growth and development are controlled by specific genes and molecular signals.
research Hair Keratin Pattern in Human Hair Follicles Grown In Vitro
Human hair follicles grown in vitro maintain normal keratin patterns and structure.