Follicular Hybrid Cyst With Isthmic-Catagen, Pilomatrical, and Syringocystadenoma Papilliferum Components
June 2012
in “
American Journal of Dermatopathology
”
Studysummary This case study describes a rare cutaneous follicular hybrid cyst intimately associated with syringocystadenoma papilliferum, proposing a potential relationship with the infrainfundibulum based on keratin expression.
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The document described a rare case of a follicular hybrid cyst (HC) in a 47-year-old man, which combined isthmic-catagen, pilomatrical, and syringocystadenoma papilliferum (SCAP) components. The cyst, located in the neck, was surgically excised and analyzed. It exhibited trichilemmal keratinization and ghost cells, indicating a mix of follicular differentiations. The study highlighted the strong expression of keratin 17 in the cyst's verrucous outgrowth, suggesting its origin from the outer root sheath or infrainfundibulum. The findings supported the relationship between SCAP and the infrainfundibulum, contributing to the understanding of epithelial combinations in follicular HCs.
