Morphological and Histochemical Studies of Skin, Mucous Membranes, and Claws in Pigs with Experimental Biotin Deficiency

September 1981 in “ Zentralblatt für Veterinärmedizin Reihe A ”

H. Geyer, Joachim Pohlenz, L. Völker

biotin deficiency hair loss stratum corneum inner root sheath hair follicles necrosis epithelium

Studysummary In this animal study, pigs on a biotin-deficient diet showed significant hair loss, weak and brittle claws, and skin lesions after 8–10 weeks, with tissue necrosis observed microscopically after 15 weeks.

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