New Drugs: Iobenguane Sulfate

    October 2004 in “ Australian Prescriber ”
    From the encyclopedia
    Finasteride →

    Frontline, gold standard treatment for combatting androgenic alopecia

    Metformin →

    diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

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    Studysummary This discussion reviews the lack of long-term clinical studies on metformin's cardiovascular benefits in women with polycystic ovary syndrome, advocating for lifestyle changes to improve insulin sensitivity. Our plain-language summary of this paper — not a Tressless recommendation.
    The document discussed the management of hirsutism and the long-term risks associated with insulin resistance, particularly in women with polycystic ovary syndrome (PCOS). It noted that while drugs like flutamide and finasteride were not commonly used in Australia due to potential side effects such as hepatotoxicity and teratogenicity, lifestyle changes were emphasized as more effective than metformin in reducing the incidence of type 2 diabetes, according to the Diabetes Prevention Program Research Group. There were no long-term clinical studies available to assess the cardiovascular benefits of metformin in women with PCOS.
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