New Drugs: Iobenguane Sulfate
October 2004
in “
Australian Prescriber
”
TLDR Lifestyle changes are more effective than metformin in reducing type 2 diabetes risk in women with PCOS.
The document discussed the management of hirsutism and the long-term risks associated with insulin resistance, particularly in women with polycystic ovary syndrome (PCOS). It noted that while drugs like flutamide and finasteride were not commonly used in Australia due to potential side effects such as hepatotoxicity and teratogenicity, lifestyle changes were emphasized as more effective than metformin in reducing the incidence of type 2 diabetes, according to the Diabetes Prevention Program Research Group. There were no long-term clinical studies available to assess the cardiovascular benefits of metformin in women with PCOS.
