Alternative Synthesis of the Anti-Baldness Compound RU58841

    January 2014 in “ RSC Advances ”
    Matthew K. Leonard, Anthony R. Lingham, Julie O. Niere … Helmut M. Hügel
    Studysummary A new, less toxic and more efficient method to create the anti-baldness compound RU58841 was developed in 2014.
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    Research cited in this study 3

    1. A Controlled Study of the Effects of RU58841, a Non-Steroidal Antiandrogen, on Human Hair Production by Balding Scalp Grafts Maintained on Testosterone-Conditioned Nude Mice British Journal of Dermatology · 1997
    2. Preliminary Pharmacokinetics and Metabolism of Novel Non-Steroidal Antiandrogens in the Rat: Relation of Their Systemic Activity to the Formation of a Common Metabolite The Journal of Steroid Biochemistry and Molecular Biology · 1994
    3. RU 58841, A New Specific Topical Antiandrogen: A Candidate of Choice for the Treatment of Acne, Androgenetic Alopecia, and Hirsutism The Journal of Steroid Biochemistry and Molecular Biology · 1994