Collagen Triple Helix Repeat Containing-1 Promotes Functional Recovery of Sweat Glands by Inducing Adjacent Microvascular Network Reconstruction In Vivo

    January 2022 in “ Burns & Trauma ”
    Xingyu Yuan, Xianlan Duan, Li Zhao … Xiaobing Fu
    Studysummary This study found that CTHRC1 is crucial for sweat gland function and vascular network integrity in mice, and its administration improved sweat gland performance by reconstructing nearby blood vessels.
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    Research cited in this study 4

    1. The Role of CTHRC1 in Hair Follicle Regenerative Capacity Restored by Plantar Dermis Homogenate Biochemical and Biophysical Research Communications · 2021
    2. Using Bioprinting and Spheroid Culture to Create a Skin Model with Sweat Glands and Hair Follicles Burns & Trauma · 2021
    3. Functional Redundancy of Frizzled 3 and Frizzled 6 in Planar Cell Polarity Control of Mouse Hair Follicles Development · 2018
    4. Identification of Stem Cell Populations in Sweat Glands and Ducts Reveals Roles in Homeostasis and Wound Repair Cell · 2012