3,3-Diphenylpentane Skeleton as a Steroid Skeleton Substitute: Novel Inhibitors of Human 5α-Reductase 1

    Shinnosuke Hosoda, Yuichi Hashimoto
    Studysummary This study developed a new competitive 5alpha-reductase inhibitor with an IC(50) of 0.84 microM using a novel chemical structure.
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    1. Finasteride in the Treatment of Androgenetic Alopecia Expert Opinion on Pharmacotherapy · 2004
    2. Treatment of Hair Loss The New England Journal of Medicine · 1999
    3. Finasteride The New England Journal of Medicine · 1994
    4. The Effect of Finasteride in Men with Benign Prostatic Hyperplasia The New England Journal of Medicine · 1992