MSCs-Exosomes in Regenerative Medicine: Current Evidence and Future Perspectives

    January 2022 in “ Biocell ”
    Benshuai You, HUI QIAN
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    TLDR Exosomes from mesenchymal stem cells show promise for tissue repair but face challenges in isolation and safety testing.
    The document discusses the role of exosomes, particularly those derived from mesenchymal stem cells (MSCs-exosomes), in regenerative medicine. These MSCs-exosomes have demonstrated anti-inflammatory, anti-oxidant, anti-apoptosis, and tissue regeneration effects in various tissue injury repair models. They possess beneficial properties such as low immunogenicity, biocompatibility, and targeting capability, making them promising in the field of regenerative medicine. However, challenges remain in areas like exosomes isolation, clinical trials, and safety evaluation.
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