Optimization of Traditional Herbal Formula for Hair Growth from East Nusa Tenggara Using Orthogonal Stimulus Response Method on Hair Density in Mice (Mus musculus)
December 2025
in “
Bioscientist Jurnal Ilmiah Biologi
”
Studysummary In this study, researchers developed an optimized formulation of a traditional ethnomedicinal recipe from East Nusa Tenggara, which demonstrated strong antioxidant activity and significantly enhanced hair growth in a mouse alopecia model, compared to control groups.
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This study optimized a traditional herbal formula from East Nusa Tenggara (RENTT) for hair growth using the Taguchi-Orthogonal Stimulus Response Method, demonstrating significant antioxidant activity and effectiveness in increasing hair density in mice with induced alopecia. The optimal RENTT formula, particularly influenced by Ficus benjamina, showed strong antioxidant properties with an IC₅₀ value of 27.46 ppm and outperformed control groups in hair density, suggesting its potential as a natural cosmeceutical product. Further research is needed to explore its phytochemical composition, safety, and efficacy in humans.
