TLDR Monilethrix Syndrome causes fragile, beaded hair that breaks easily and needs early diagnosis for better care.
The document discussed Monilethrix Syndrome, a rare genetic condition characterized by beaded or moniliform hair, which is fragile and prone to breakage. The syndrome often presented in childhood and could be associated with other ectodermal abnormalities. The authors, K. Despontin and B. Krafchik, from the Hospital for Sick Children in Toronto, Ontario, Canada, provided clinical insights and diagnostic criteria for identifying this condition. The study emphasized the importance of recognizing the syndrome early for better management and care of affected individuals.
26 citations,
May 1991 in “Clinical and experimental dermatology” Oral etretinate improved hair length and reduced beading in monilethrix.
13 citations,
January 1991 in “Dermatology” Minoxidil helps hair growth in people with monilethrix without side effects.
24 citations,
July 1983 in “Clinical and Experimental Dermatology” Tigason improved hair growth in a boy with monilethrix without side effects.
89 citations,
September 2010 in “Annual Review of Genomics and Human Genetics” The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
1 citations,
February 2013 in “InTech eBooks” Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.
41 citations,
November 2011 in “The Journal of Dermatology” Some hair loss disorders are caused by genetic mutations affecting hair growth.
2 citations,
January 2013 in “Elsevier eBooks” The document explains the genetic causes and characteristics of inherited hair disorders.
26 citations,
July 2019 in “Dermatology and Therapy” The conclusion is that genetic testing is important for diagnosing and treating various genetic hair disorders.
