TLDR Merkel cell increase is specific to certain skin diseases, not general skin growth.
The study investigated the distribution of Merkel cells in 165 skin lesions using a monoclonal antibody to keratin 20. It found that Merkel cell numbers were frequently increased in conditions such as actinic keratosis, fibrous papules of the face, and some lesions with immature hair follicle differentiation. The conclusion suggested that Merkel cell hyperplasia was not related to general epidermal proliferation but was specific to certain skin diseases.
149 citations
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July 2000 in “Molecular and Cellular Biology” Keratin 6a is important for quick wound healing from hair follicles.
24 citations
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January 1998 in “Dermatology” Merkel cell increase is specific to certain skin diseases, not general skin growth.
28 citations
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September 1995 in “Biochemistry and Cell Biology” Merkel cells are more densely found in hairless skin areas like palms and soles.
61 citations
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August 1993 in “PubMed” Basal cell epithelioma likely starts from the hair follicle's outer root sheath.
9 citations
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January 1990 in “Skin Pharmacology and Physiology” The method and source of keratinocytes affect the structure of reconstructed skin.
198 citations
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November 1989 in “The Journal of Cell Biology” Keratin K14 expression varies between hair follicles and epidermis, affecting cell differentiation.
2 citations
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January 1989 Researchers developed a method to grow skin-like tissue from hair cells.
