Introduction And Summary Of Findings On Melatonin's Photoprotective Properties

This 1972 review examined clinical studies on the topical application of melatonin, highlighting its potential as a photoprotective agent due to its antioxidant and anti-inflammatory properties. The studies, which were well-designed (randomized, double-blind, and placebo-controlled), supported melatonin's efficacy in preventing skin damage from radiation. However, the evidence for its effectiveness as an anti-aging or hair growth-promoting agent was inconclusive, largely due to study design limitations and the use of additional active ingredients. One trial indicated a potential benefit for treating alopecia in women, but further research was needed to confirm melatonin's role in skin aging and hair loss prevention.