Absence of Male-Pattern Baldness in Men with X-Linked Recessive Ichthyosis
January 1999
in “
Dermatology
”
Studysummary This hypothesis paper proposes that men with X-linked recessive ichthyosis may exhibit no androgenetic alopecia or only mild forms, and suggests clinical studies to evaluate this hypothesis.
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The document hypothesized that men with X-linked recessive ichthyosis (XRI), a condition caused by a deficiency of steroid sulfatase, did not exhibit androgenetic alopecia or only developed mild forms of this type of hair loss. This hypothesis was based on the role of steroid sulfatase in androgen metabolism. The document suggested that clinical studies were needed to determine if this hypothesis could be supported.