In this study, the researchers developed a biomimetic multilayer composite scaffold combining a decellularized amniotic membrane, fibroblast-laden collagen gel, and epidermal stem cells, which healed full-thickness skin wounds more quickly and effectively by regenerating hair follicles without scarring compared to Moropicin ointment.
3 citations
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November 2021 in “Journal of biomedical materials research. Part B, Applied biomaterials” In a rabbit model, this study found that the AMFIBHA skin substitute promoted wound healing and regeneration of skin structures in large-area third-degree burn wounds, suggesting potential clinical use.
January 2025 in “Open Veterinary Journal” This study investigated tissue healing in cats with auto skin grafts, finding that those treated with a combination of platelet-rich plasma and tilapia skin bio-dressings showed improved tissue structure, reduced collagen density, and more widespread caspase-3 expression compared to other treatments.
21 citations
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February 2015 in “Journal of Feline Medicine and Surgery” This study found that negative pressure wound therapy combined with skin grafting is a feasible method for treating soft tissue and skin defects in cats, achieving a high graft take rate and satisfactory outcomes.
June 2026 in “Materials Today Bio” This study reported that a decellularized porcine amniotic membrane hydrogel can alleviate inflammation and promote tissue repair in a UVB-induced skin inflammation model, suggesting its potential as a regenerative treatment for photodamage-associated skin injuries.