Clinical Evaluation of Hair Regrowth Tonics Containing Oleanolic Acid

    January 1989 in “ Skin research
    Mari Suzuki, Yoshimi Ninagawa, Kazuya Hosokawa, Kayoko Matsunaga, Ritsuko Hayakawa, Eiji Fukushima, Hiroshi Ueda
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    Studysummary In this study, an oleanolic acid-containing scalp treatment increased terminal hair counts significantly more than placebo in men under 50 with androgenic alopecia, but only three showed clinical improvement, with minimal side effects reported.
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    The study evaluated a hair regrowth tonic containing 22.5% swertia extract with oleanolic acid on 14 males under 50 with male pattern baldness. After 4 months, the treated areas showed a significant increase in hair count, while placebo areas did not. Clinically significant effects were observed in 3 patients, and only 1 patient experienced mild itching. The tonic was deemed effective and safe for treating male pattern baldness.
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