Lichen Planopilaris Treated With Thalidomide

    December 2001 in “ Journal of the American Academy of Dermatology ”
    Saira George, Sylvia Hsu
    TLDR Thalidomide significantly improved hair regrowth in a woman with lichen planopilaris.
    A 41-year-old woman with lichen planopilaris, a scarring alopecia, showed no improvement with initial treatments including steroids and hydroxychloroquine. She was then treated with oral thalidomide, 150 mg daily, which led to significant hair regrowth within 1 month. The dosage was tapered to 50 mg daily for another month, and the patient did not return for follow-up after 18 months. Thalidomide has shown promise in treating inflammatory skin disorders like lichen planopilaris, likely due to its anti-inflammatory effects, despite its potential side effects and risks.
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