This study investigates lichen planopilaris (LPP) in 24 African American women, challenging the notion that scarring alopecia in Black women is mainly central cicatricial centrifugal alopecia. It introduces the "arrowhead distribution" pattern as a potential indicator of progressive scarring alopecia in LPP, distinct from other forms. The study underscores the importance of considering LPP in the differential diagnosis for Black patients with scarring alopecia, recommending biopsy confirmation to prevent treatment delays and improve outcomes. Findings revealed that 91.7% of patients had vertex involvement, and 70.8% had both frontal and vertex involvement, with common trichoscopic findings of perifollicular erythema and scale. The study calls for further research to better understand and differentiate alopecias in Black patients.
30 citations
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January 2020 in “Journal of The American Academy of Dermatology” Fibrosing alopecia in a pattern distribution is a hair loss condition often confused with other types, requiring early treatment but usually not resulting in significant hair regrowth.
35 citations
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November 2019 in “Journal of the American Academy of Dermatology” A new variant of lichen planopilaris causing diffuse hair thinning was identified.
48 citations
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November 2018 in “Journal of dermatological treatment” Women are more likely to have Lichen planopilaris, and treatments with cyclosporine and methotrexate are most effective but less safe than mycophenolate mofetil.
95 citations
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November 2016 in “Journal of The American Academy of Dermatology” Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.
13 citations
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March 2016 in “Journal of Cutaneous Pathology” Some people's hair loss is caused by multiple factors, with the most common being a mix of AGA and CCCA.
34 citations
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April 2016 in “International Journal of Dermatology” Trichoscopy is a useful method for identifying primary cicatricial alopecias and their specific types.
57 citations
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January 2020 in “International Journal of Molecular Sciences” PADs are crucial for healthy skin and hair, and their imbalance can cause skin and hair disorders.
16 citations
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February 2010 in “Journal of the European Academy of Dermatology and Venereology” Fibrosing alopecia in a pattern distribution is a unique hair loss condition that may respond to antiandrogen therapy.
25 citations
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June 2018 in “Journal of The American Academy of Dermatology” Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.