Multi-Target Evaluation of Korean Herbal Compounds Against the SRD5A2 / AR / Beta-Catenin Axis for Androgenetic Alopecia: Boltz-2 Cofold, ChEMBL-Anchored Ranking, ADMET-AI 107-Endpoint Safety Panel, and Pilosebaceous Single-Cell Atlas-Constrained Prioritization of Saponin Re, Emodin, and Biochanin A
May 2026
in “
Open Science Framework
”
Studysummary This study conducted an in silico evaluation of Korean herbal compounds against key targets involved in androgenetic alopecia, finding Biochanin A, Saponin Re, and Emodin as promising candidates for topical treatments, but highlighting safety and topical formulation challenges.
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