TLDR Mutations in keratin genes may link hair disorders to dental decay.
The research revealed an unexpected link between hair disorders and dental decay through the study of keratins, which are structural proteins in hair, nails, and the skin's outer layer. The study suggested that mutations in keratin genes, which are known to cause certain hair disorders, might also contribute to dental decay. This connection was supported by findings that individuals with specific hair disorders often exhibited higher rates of dental issues. The study highlighted the importance of keratins beyond their traditional roles, suggesting a broader impact on human health, particularly in the context of hair and dental health.
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September 2010 in “Annual Review of Genomics and Human Genetics” The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
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February 2019 in “PloS one” Bald thigh syndrome in sighthounds is caused by structural defects in hair shafts due to downregulated genes and proteins.