Tissue Regeneration, Stem Cells, And Wound Healing

January 2012 in “ Journal of Investigative Dermatology ”

Tiede, S., Lehmann, J., Liao, T. … Paus, R.

hair follicle neogenesis prostaglandin D2 PGD2 human dermal papilla cells Wnt signaling hair regeneration therapies skin regeneration tissue regeneration wound healing hair loss

Studysummary Inhibiting PGD2 and using dermal papilla cells may improve skin and hair regeneration.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer ·

Read the full study on jidonline.org →

Discuss this study in the Community →

Similar research 5

Hair Follicle Regeneration Stem cell biology and regenerative medicine · 2022
Getting to the Core of the Dermal Papilla Journal of Investigative Dermatology · 2017
Proceedings of the Ninth World Congress for Hair Research 2015 Journal of Investigative Dermatology Symposium Proceedings · 2017
Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair Cell Stem Cell · 2020
Morroniside Regulates Hair Growth and Cycle Transition via Activation of the Wnt/β-Catenin Signaling Pathway Scientific Reports · 2018

Related Community Posts Join

6 / 1000+ results

community Anyone here have a lot of knowledge on hair follicle stem cells and progenitor cells for PP405?

in Chat 4 upvotes 8 months ago

Hair follicle stem cells remain in bald individuals, but progenitor cells do not, raising questions about hair regrowth claims by Pelage. PP405 is discussed as a potential treatment, with skepticism about its effectiveness compared to existing treatments like Minoxidil and Finasteride.

community New Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness - Paper entitled "Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type" published journal Developmental Cell

13 upvotes 11 years ago

A new treatment using dermal sheath cup cells may regrow hair and could require repeat treatments every 8 years. Users discuss ongoing trials and plan to use finasteride and minoxidil until the treatment is available.

community Korean scientists breakthrough in hair regeneration targeting CXXC5 protein and WNT Signaling Pathway

53 upvotes 8 years ago

A potential non-invasive topical treatment targeting the WNT Signaling Pathway for hair regeneration is being researched, with positive results on human hair follicle cells. Current effective treatments for hair loss include Minoxidil, finasteride, and hair transplantation.

community Hair follicle dermal papilla exosomes

2 upvotes 1 year ago

The conversation discusses using hair follicle dermal papilla exosomes for hair loss treatment. It inquires about purchasing options for this treatment.

community Fully functional hair follicle regeneration through the rearrangement of stem cells and their niches

4 upvotes 11 years ago

Hair follicle regeneration through stem cell rearrangement is discussed, focusing on bioengineered cellular structures rather than traditional hair transplants. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Pelage PP405: New Hair Growth from Inactive Follicular Units - Phase 2a results at AAD 2026

1080 upvotes 5 months ago

PP405, a topical treatment, shows promise for hair growth by activating inactive follicles, with 66% of participants experiencing positive results. The treatment is well-tolerated and may proceed directly to Phase 3 trials, offering a potential alternative to minoxidil and finasteride.