Is the Comb Over Dying? A Mouse Model for Male Pattern Baldness (Androgenic Alopecia)

    April 2010 in “ Endocrinology ”
    William F. Walker
    Studysummary This review discusses the mechanisms of androgenic alopecia and reports no new results; the development of a mouse model for further study is described.
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    Research cited in this study 7

    1. A Mouse Model of Androgenetic Alopecia Endocrinology · 2010
    2. Keratinocyte Growth Inhibition Through the Modification of Wnt Signaling by Androgen in Balding Dermal Papilla Cells ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 2009
    3. Molecular Mechanisms of Androgenetic Alopecia Experimental Gerontology · 2002
    4. Treatment of Hair Loss The New England Journal of Medicine · 1999
    5. Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia Journal of Investigative Dermatology · 1997
    6. Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia Dermatologic Clinics · 1996
    7. Cultured Dermal Papilla Cells From Androgen-Dependent Human Hair Follicles Contain More Androgen Receptors Than Those From Non-Balding Areas Of Scalp Journal of Endocrinology/Journal of endocrinology · 1992