Interleukin 17 Expression in Psoriatic Skin Lesions before and after Treatment with Platelet Rich Plasma (PrP)

    Musa Mohammed, M.D. NADER A. ISMAIL SAHAR F. MANSOUR
    TLDR Platelet Rich Plasma reduces psoriasis symptoms but isn't enough alone for treatment.
    This study investigated the effect of Platelet Rich Plasma (PrP) on Interleukin 17 (IL17) expression in psoriatic skin lesions in 24 patients. PrP injections led to significant reductions in clinical parameters such as size, erythema, thickness, and scaling of psoriatic plaques, while saline injections only reduced scaling. Additionally, 6 out of 9 IL17-positive plaques became IL17-negative after PrP treatment, whereas all plaques remained IL17-positive with saline. Despite these improvements, PrP alone was not deemed sufficient as a standalone treatment for localized plaque psoriasis.
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      community Thoughts on platelet-rich plasma therapy

      in Treatment  3 upvotes 1 year ago
      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

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      in Treatment  6 upvotes 1 year ago
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      in Treatment  3 upvotes 3 years ago
      Hair loss discussion includes treatments like Minoxidil, finasteride, and RU58841. Platelet rich plasma treatment is considered expensive but cheaper than hair transplant.

      community PRP ( PLATELET-RICH-PlASMA) for hair loss

      in Treatment  1 upvotes 2 years ago
      A 27-year-old male experiencing hair loss post-Covid is considering PRP (platelet-rich plasma) therapy. He's seeking personal experiences about the process, particularly regarding pain levels, despite his dermatologist's assurance of using local anesthesia.

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      in Research/Science  14 upvotes 2 years ago
      Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

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