Advances in Innovative Surgical Implant Manufacturing for Hernia Repair and Soft Tissue Reconstruction

The document discusses the challenges and advancements in surgical implant manufacturing for hernia repair, emphasizing the role of regenerative medicine. Despite improvements in surgical techniques and meshes, complications remain prevalent. Regenerative medicine, using scaffolds, platelet-rich plasma (PRP), and stem cells, aims to enhance tissue repair and regeneration. Ischemia is identified as a major risk factor affecting cell survival on prosthetic materials. The review hypothesizes that coating surgical meshes with PRP could enhance neoangiogenesis and create favorable conditions for cell proliferation and differentiation, potentially improving outcomes in hernia repair and soft tissue reconstruction.