Supplementary Material for: Immunotherapy-Induced Scarring Alopecia: A Case Series

    March 2026 in “ Figshare
    figshare admin karger, ElInkichari D., Sboui K., Donzel M., Ribereau-Gayon E., Fathallah R., N. S. DALLE
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    TLDR Immune therapy for cancer can cause rare hair loss but doesn't stop treatment success.
    This case series investigates scarring alopecia in patients treated with immune checkpoint inhibitors (ICI) for metastatic melanoma. Out of 450 patients, 6 developed scarring alopecia, indicating a prevalence of 1.33%. The study focuses on 4 female patients, with a mean age of 64 years, who experienced hair loss on average 29.25 months after starting treatment. Despite the alopecia, treatment was not discontinued, and all patients had favorable cancer outcomes. The study highlights the importance of understanding immune-induced alopecia for patient awareness and suggests further research into the link between treatment efficacy and follicular toxicity.
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