Immunological Skin Diseases

January 2018

DipACVP Danny W. Scott

alopecia areata bullous pemphigoid urticaria IgG autoantibodies collagen XVII autoimmune disease hair follicles

The chapter reviewed various immunological skin diseases in pigs, including urticaria, bullous pemphigoid, alopecia areata, and porcine ulcerative dermatitis syndrome. Urticaria was described as a rare, variably pruritic skin disorder with potential immunologic or nonimmunologic causes, such as insects and infections. Bullous pemphigoid was noted as an extremely rare autoimmune disease in Yucatan minipigs, involving IgG autoantibodies targeting collagen XVII. Alopecia areata was identified as a very rare autoimmune condition affecting hair follicles through cell-mediated and humoral responses.

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