Immunological Skin Diseases

January 2018

DipACVP Danny W. Scott

alopecia areata bullous pemphigoid urticaria IgG autoantibodies collagen XVII autoimmune disease hair follicles

TLDR Immunological skin diseases in pigs are rare and can be caused by immune system issues or external factors.

The chapter discussed various immunological skin diseases in pigs, including urticaria, bullous pemphigoid, alopecia areata, and porcine ulcerative dermatitis syndrome. Urticaria was described as a rare, variably pruritic, and edematous skin disorder with potential immunologic or nonimmunologic causes such as insects, infections, and medications. Bullous pemphigoid was noted as an extremely rare autoimmune disease in adult Yucatan minipigs, involving IgG autoantibodies targeting collagen XVII. Alopecia areata was identified as a very rare autoimmune dermatosis, where anagen hair follicle antigens are targeted by autoimmune responses.

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