Human Hair Follicle Regeneration Following Amputation and Grafting into the Nude Mouse
December 1996
in “Journal of Investigative Dermatology”
TLDR Human hair follicles can regenerate after removal, but with low success rate.
This study from 1996 investigated the ability of human hair follicles to regenerate after amputation and transplantation onto athymic mice. The results showed that human hair follicles have the capacity to regenerate after removal, but the success rate was relatively low. The study emphasizes the importance of specific cellular subpopulations within the follicle and the role of dermal-epidermal interactions in adult follicle activities. The study suggests that the human hair follicle has the potential for regeneration, but further research is needed to improve the success rate.
View this study on jidonline.org →
Cited in this study
research Cellular and extracellular involvement in the regeneration of the rat lower vibrissa follicle
Both cell and non-cell parts are important for rat whisker follicle regrowth.
research Reduced Linear Hair Growth Rates of Vellus and of Terminal Hairs Produced by Human Balding Scalp Grafted onto Nude Mice
Related
research Hair-follicle dermal papilla and sheath fibroblasts provide a supportive microenvironment for human skin regeneration
Certain cells around hair follicles help improve skin regeneration for potential use in skin grafts.
research Effect of age and sex on fiber and follicle characteristics of an Iranian native sheep
As sheep age, their hair fibers and follicles grow larger and more organized, with no significant differences between males and females.
research Is the “Comb Over” Dying? A Mouse Model for Male Pattern Baldness (Androgenic Alopecia)
The mouse model suggests male pattern baldness may be due to an enzyme increasing DHT and higher androgen receptor levels in hair follicles.
research Histological Study of Reconstructed Hair Follicles
research Human Hair Follicle Regeneration Following Amputation and Grafting into the Nude Mouse
Human hair follicles can regenerate after removal, but with low success rate.
research The upper dermal sheath has a potential to regenerate the hair in the rat follicular epidermis
The upper dermal sheath can regenerate hair in rats.