Health-Related Quality of Life (HRQoL) Among Patients With Primary Cicatricial Alopecia (PCA): A Systematic Review

    Rashmi Singh, Doris Wilborn, Dimitra‐Aikaterini Lintzeri, Ulrike Blume‐Peytavi
    TLDR Primary cicatricial alopecia significantly reduces life quality, mainly due to pain and anxiety.
    This systematic review evaluates the health-related quality of life (hrQoL) in patients with primary cicatricial alopecia (PCA), involving 572 patients across 14 studies. It reveals significant emotional and mental health challenges, with PCA patients experiencing worse quality of life compared to healthy controls, particularly in self-esteem, mental health, and physical functioning. The review highlights potential biases in the studies and suggests the need for more robust research. It emphasizes the importance of comprehensive assessment and management strategies, including mental health support and interventions like prescribing wigs, to address the psychosocial burden of PCA. Further research using standardized tools is recommended to better understand the psychological impact and support needs of PCA patients.
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