Hirsutism: Clinical, Biological, and Etiological Aspects (Regarding 20 Cases)

    September 2013 in “ Annales d Endocrinologie
    F. Aziouaz, S. Bensbaa, I. Damoune, I. Yassine, F. Ajdi
    TLDR Hirsutism often links to polycystic ovary syndrome and high testosterone, needing thorough investigation.
    This study aimed to determine the clinical, biological, and etiological aspects of hirsutism through a retrospective analysis of 20 patients from January 2009 to March 2013. The average age of the patients was 27 years, with hirsutism appearing during puberty in 26% and post-puberty in 73%. The condition was mild in 50% and moderate in 50% of cases, with 33% experiencing menstrual cycle disorders. Hyperandrogenism was present in 45% of patients, and 20% showed signs of hypercorticism. Obesity was noted in 45% of cases, with 25% being overweight. Other associated conditions included hypertension (30%), diabetes (15%), glucose intolerance (10%), hyperinsulinism (10%), and dyslipidemia (20%). Elevated testosterone levels were found in 75% of cases. The etiologies included polycystic ovary syndrome (45%), idiopathic causes (25%), enzymatic block (15%), medication-related (10%), and adrenal tumors (5%). The study highlighted the importance of a thorough etiological investigation and recommended measuring total testosterone as a first step.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 27 results

      community Dutasteride is amazing even for women with FAGA!

      in Female  151 upvotes 3 months ago
      Dutasteride significantly improved hair health and reduced shedding for a woman with PCOS and hyperandrogenism, without causing depression or anxiety, unlike finasteride. Dutasteride also helped with PMDD symptoms and had no side effects, though it changed hair texture.

      community DHT levels after 4 weeks of Fina and 8 weeks of Fina + 4 weeks of Duta

      in Update  36 upvotes 6 years ago
      The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.

      community AA and Hirsutism but T levels are normal

      in Female  6 upvotes 4 years ago
      27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

      community Finasteride 5mg & Spironolactone 100mg

      in Female  2 upvotes 1 year ago
      A 20-year-old female is using finasteride 5mg and spironolactone 100mg for severe hirsutism and is experiencing minor side effects like water weight loss and irregular periods. She is concerned about potential future side effects and hair regrowth on her scalp.

      community No, Finasteride as a treatment for MPB was not an "accident"

      in Research/Science  107 upvotes 4 years ago
      Finasteride was intentionally developed to treat BPH and later approved for male pattern baldness (MPB) due to its 5AR inhibition effects. The delay in MPB approval was due to concerns about off-label use for female hirsutism and the prioritization of treating a more debilitating condition.

      community Coegin Pharma to release Follicopeptide (FOL005) by Q2 2025

      in Treatment  121 upvotes 1 year ago
      Follicopeptide (FOL005) by Coegin Pharma will launch as a cosmetic hair growth treatment by Q2 2025, showing similar efficacy to finasteride. Users discuss the benefits and skepticism of releasing hair loss treatments as cosmetics rather than drugs.

    Similar Research

    5 / 1000+ results