Hirsutism: Clinical, Biological, and Etiological Aspects (Regarding 20 Cases)

    September 2013 in “ Annales d Endocrinologie
    F. Aziouaz, S. Bensbaa, I. Damoune, I. Yassine, F. Ajdi
    TLDR Hirsutism often links to polycystic ovary syndrome and high testosterone, needing thorough investigation.
    This study aimed to determine the clinical, biological, and etiological aspects of hirsutism through a retrospective analysis of 20 patients from January 2009 to March 2013. The average age of the patients was 27 years, with hirsutism appearing during puberty in 26% and post-puberty in 73%. The condition was mild in 50% and moderate in 50% of cases, with 33% experiencing menstrual cycle disorders. Hyperandrogenism was present in 45% of patients, and 20% showed signs of hypercorticism. Obesity was noted in 45% of cases, with 25% being overweight. Other associated conditions included hypertension (30%), diabetes (15%), glucose intolerance (10%), hyperinsulinism (10%), and dyslipidemia (20%). Elevated testosterone levels were found in 75% of cases. The etiologies included polycystic ovary syndrome (45%), idiopathic causes (25%), enzymatic block (15%), medication-related (10%), and adrenal tumors (5%). The study highlighted the importance of a thorough etiological investigation and recommended measuring total testosterone as a first step.
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